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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK2
All Species:
28.48
Human Site:
S442
Identified Species:
62.67
UniProt:
Q8N568
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N568
NP_001035350.2
766
83612
S442
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Chimpanzee
Pan troglodytes
XP_001150968
766
83601
S442
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
S459
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Dog
Lupus familis
XP_539760
862
93767
S459
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGN3
756
82960
S441
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Rat
Rattus norvegicus
Q5MPA9
767
83998
S457
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511279
630
68724
T325
M
L
I
E
E
M
D
T
S
S
E
L
Y
L
V
Chicken
Gallus gallus
XP_420439
761
82932
S439
H
L
I
E
N
E
V
S
I
L
R
R
V
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139259
791
87409
A449
H
L
I
E
N
E
V
A
V
L
R
R
V
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394386
670
74883
A365
Q
G
K
E
T
M
W
A
S
E
V
S
I
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
R356
K
N
S
A
G
S
V
R
S
K
A
L
C
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
81.9
N.A.
93.4
92.6
N.A.
71
84.5
N.A.
71.5
N.A.
N.A.
39.5
N.A.
48.6
Protein Similarity:
100
99.4
97
83.9
N.A.
95.4
95
N.A.
75.7
89.9
N.A.
82.4
N.A.
N.A.
57
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
86.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
N.A.
100
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
19
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
91
10
73
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
73
% H
% Ile:
0
0
82
0
0
0
0
0
64
0
0
0
10
0
0
% I
% Lys:
10
0
10
0
0
0
0
0
0
10
0
0
0
73
0
% K
% Leu:
0
82
0
0
0
0
0
0
0
73
0
19
0
19
0
% L
% Met:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
73
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
73
73
0
10
10
% R
% Ser:
0
0
10
0
0
10
0
64
28
10
0
10
0
0
10
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
82
0
10
0
10
0
73
0
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _